William C Eckelman Selected Research

Antigens

1/2020	[68Ga]Ga-P16-093 as a PSMA-Targeted PET Radiopharmaceutical for Detection of Cancer: Initial Evaluation and Comparison with [68Ga]Ga-PSMA-11 in Prostate Cancer Patients Presenting with Biochemical Recurrence.
8/2013	99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer.
3/2013	Synthesis and SAR of ⁹⁹mTc/Re-labeled small molecule prostate specific membrane antigen inhibitors with novel polar chelates.
3/2013	First-in-man evaluation of 2 high-affinity PSMA-avid small molecules for imaging prostate cancer.
7/2011	123I-MIP-1072, a small-molecule inhibitor of prostate-specific membrane antigen, is effective at monitoring tumor response to taxane therapy.
9/2009	Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

William C Eckelman Research Topics

Disease

13	Neoplasms (Cancer) 01/2020 - 10/2002
6	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 09/2009
4	Disease Progression 04/2014 - 06/2008
3	Alzheimer Disease (Alzheimer's Disease) 09/2008 - 09/2003
3	Fibrosis (Cirrhosis) 06/2008 - 08/2005
2	Heart Diseases (Heart Disease) 06/2015 - 06/2008
2	Neuroinflammatory Diseases 09/2012 - 09/2008
2	Heart Failure 06/2008 - 04/2007
2	Hypoxia (Hypoxemia) 04/2007 - 10/2006
1	Inflammation (Inflammations) 09/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 09/2022
1	Mental Disorders (Mental Disorder) 09/2022
1	Infections 04/2014
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2007
1	Cardiomyopathies (Cardiomyopathy) 02/2007
1	Major Depressive Disorder (Major Depressive Disorders) 07/2006
1	Bipolar Disorder (Manic Depressive Psychosis) 07/2006
1	Glioma (Gliomas) 11/2005
1	Atrophy 07/2005
1	Temporal Lobe Epilepsy 07/2005
1	T-Cell Leukemia (Leukemia, T Cell) 04/2004
1	Memory Disorders (Memory Loss) 09/2003
1	Breast Neoplasms (Breast Cancer) 10/2002
1	Stroke (Strokes) 01/2002

Drug/Important Bio-Agent (IBA)

6	AntigensIBA 01/2020 - 09/2009
5	RadiopharmaceuticalsIBA 01/2020 - 01/2003
4	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 06/2008 - 08/2005
2	Proteins (Proteins, Gene)FDA Link 09/2022 - 07/2011
2	2-(phosphonomethyl)pentanedioic acidIBA 08/2013 - 09/2009
2	Arachidonic Acid (Vitamin F)IBA 09/2012 - 09/2008
2	Paclitaxel (Taxol)FDA LinkGeneric 07/2011 - 06/2007
2	Lysine (L-Lysine)FDA Link 06/2010 - 09/2009
2	Biomarkers (Surrogate Marker)IBA 09/2008 - 11/2005
2	Angiotensin IIIBA 04/2007 - 08/2005
2	Cholinergic Agents (Cholinergics)IBA 07/2006 - 09/2003
2	FP-TZTPIBA 07/2006 - 11/2003
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 06/2015
1	Adrenergic Receptors (Adrenergic Receptor)IBA 06/2015
1	RheniumIBA 03/2013
1	Carbonic Anhydrase IXIBA 01/2013
1	Phospholipids (Phosphatides)FDA LinkGeneric 09/2012
1	taxaneIBA 07/2011
1	LigandsIBA 06/2010
1	Octreotide (Sandostatin)FDA LinkGeneric 06/2010
1	glutamate carboxypeptidaseIBA 09/2009
1	Glutamic Acid (Glutamate)FDA Link 09/2009
1	Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)IBA 09/2009
1	Urea (Carbamide)FDA LinkGeneric 09/2009
1	2- (3- (1- carboxy- 5- (3- (4- iodobphenyl)ureido)pentyl)ureido)pentanedioic acidIBA 09/2009
1	2- (3- (1- carboxy- 5- (4- iodobenzylamino)pentyl)ureido)pentanedioic acidIBA 09/2009
1	copper (II) diacetyl- di(N(4)- methylthiosemicarbazone)IBA 04/2007
1	carbogenIBA 04/2007
1	NitroimidazolesIBA 04/2007
1	fluoromisonidazoleIBA 04/2007
1	Oxygen (Dioxygen)IBA 04/2007
1	Peptides (Polypeptides)IBA 04/2007
1	pimonidazoleIBA 04/2007
1	Lisinopril (Prinivil)FDA LinkGeneric 02/2007
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 10/2006
1	Hypoxia-Inducible Factor 1IBA 10/2006
1	IsoenzymesIBA 10/2006
1	fluorodopa F 18IBA 07/2006
1	Muscarinic M2 ReceptorIBA 07/2006
1	Acetylcholine (Acetylcholine Chloride)FDA Link 07/2006
1	UracilIBA 11/2005
1	Thymidine KinaseIBA 11/2005
1	Green Fluorescent ProteinsIBA 11/2005
1	Serotonin (5 Hydroxytryptamine)IBA 07/2005
1	Therapeutic UsesIBA 05/2004
1	BismuthIBA 05/2004
1	Biotin (Vitamin H)FDA Link 05/2004
1	Monoclonal AntibodiesIBA 05/2004
1	Interleukin-2 Receptors (IL 2 Receptor)IBA 04/2004
1	Muscarinic AgonistsIBA 11/2003
1	ApolipoproteinsIBA 09/2003
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 08/2003
1	Glucose (Dextrose)FDA LinkGeneric 10/2002
1	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA 10/2002
1	Vasoactive Intestinal Peptide Receptors (Vasoactive Intestinal Peptide Receptor)IBA 10/2002
1	arginylarginine (Arg-Arg)IBA 10/2002
1	BMS204352IBA 01/2002

Therapy/Procedure

4	Therapeutics 04/2014 - 11/2005
1	Intravenous Administration 01/2020
1	Drug Therapy (Chemotherapy) 07/2011
1	Precision Medicine 09/2008
1	Radiotherapy 10/2006
1	Organ Transplantation 04/2004